Current Job Opportunities
The Department of Statistics (www.stat.ubc.ca) and the Centre for Molecular Medicine and Therapeutics (www.cmmt.ubc.ca) at the University of British Columbia (www.ubc.ca) seek applications for a Research Associate in Bioinformatics and Computational Biology.
The successful candidate will lead the research on developing and applying computational and statistical approaches to combine multiple types of genomics data (including whole genome sequencing, metabolomics, and DNA methylation data), with the goal of identifying disease mechanisms and biomarkers, along with treatment targets, to improve patient outcomes. This translational work requires close interaction with BC Children’s Hospital clinicians to understand the phenotypes of patients.
This project builds upon the success of the TIDEx project at BCCH, which through implementation of state-of-the-art sequencing and computational approaches in a clinical setting has pioneered the discovery of multiple confirmed rare-human-disease genes and pathways.
The ideal candidate will also pursue research on statistical data integration of multi-omics data in the context of common neurological disease. In this direction, the candidate will work with members of the Mostafavi lab and collaborators at Brigham’s Women’s Hospital in Boston to develop and apply methods for combining genotyping data, RNA-sequencing gene expression data, and DNA methylation data in the context of Multiple Sclerosis and Alzheimer’s Disease.
• Conduct research and supervise projects in the area of Applied Genome Analysis.
• Develop and apply methods for the identification of disease causing variations in genome sequences.
• Develop and apply computational methods for statistical data integration of multiple types of genomics data.
• Present findings at local, national and international scientific meetings where the impression can have direct influence on future scientific funding.
• Assist in the development of grant and scholarship applications related to the research.
• Work with principal investigator to ensure that all scientific milestones are achieved.
• Ph.D. degree in a life sciences discipline, Bioinformatics, or Computational Biology.
• A minimum of 2 years’ demonstrated experience in bioinformatics with focus on analysis of genomics data.
• A background in molecular biology and familiarity with bioinformatics tools and techniques would be a strong asset.
• Familiarity with metabolomics data and analysis tools.
• Knowledge of bioinformatics, with emphasis on genome sequence analysis and gene annotation.
• Knowledge of scientific tools, technologies and online resources for gene disease relationship prediction.
• A scripting programming language like Python or Perl.
• A programming language for data manipulation and computational modeling, like R or MATLAB.
• Experience with the Linux environment.
• Experience with computer clusters.
• SQL database use via API interfaces.
• Experience with gene network analysis tools.
• Experience with project management tools, like Git and GitHub.
The position is subject to final budgetary approval. The successful candidate will be appointed for one year, with the possibility of renewal. The position will be available in July 2016.
Applicants should send a cover letter and curriculum vitae to Sara Mostafavi (firstname.lastname@example.org) by the closing date Wednesday, July 20, 2016 at 4:30 pm PST. Due to the number of applications we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of competitions except to those who are selected for an interview.
UBC hires on the basis of merit and is strongly committed to equity and diversity within its community. We especially welcome applications from visible minority group members, women, Aboriginal persons, persons with disabilities, persons of minority sexual orientations and gender identities, and others with the skills and knowledge to productively engage with diverse communities. All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.