STAT 538A November 2018

Assignment 4

Due date: please submit your completed assignment by e-mail by end of the day, Thursday, Dec. 6

Question 1: From Chapter 5 in ELMR

The toenail data comes from a multicenter study comparing two oral treatments for toenail infection. Patients were evaluated for the degree of separation of the nail. Patients were randomized into two treatments and were followed over seven visits: four in the first year and yearly thereafter. The patients have not been treated prior to the first visit so this should be regarded as the baseline.

Analyze the data to determine the difference between the two treatments and the progression of the infection over time.

Question 2: From Chapter 10 in ELMR

The dataset melanoma gives data on a sample of patients suffering from melanoma (skin cancer) cross-classified by the type of cancer and the location on the body. Determine whether the type and location are independent. Examine the residuals to determine whether any dependence can be ascribed to particular type/location combinations.