@article {pmid8441164, title = {Detecting treatment effects in patients with rheumatoid arthritis: the advantage of longitudinal data}, journal = {J. Rheumatol.}, volume = {20}, number = {1}, year = {1993}, month = {Jan}, pages = {40{\textendash}44}, author = {Edworthy, S. M. and Bloch, D. A. and Brant, R. F. and Fries, J. F.} }