A scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

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  1. Department of Statistics
  2. A scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

A scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

TitleA scalable approach to topic modelling in single-cell data by approximate pseudobulk projection
Publication TypeJournal Article
Year of Publication2024
AuthorsSubedi, S, Sumida, TS, Park, YP
JournalLife science alliance
Volume7
AbstractProbabilistic topic modelling has become essential in many types of single-cell data analysis. Based on probabilistic topic assignments in each cell, we identify the latent representation of cellular states. A dictionary matrix, consisting of topic-specific gene frequency vectors, provides interpret …